Posttranscriptional Regulation of Oral Bacterial Adaptive Responses

Posttranscriptional Regulation of Intrinsic Plasticity

Transcriptional Responses of Treponema denticola to Other Oral Bacterial Species

The classic organization by Socransky and coworkers categorized the oral bacteria of the subgingival plaque into different complexes. Treponema denticola, Porphyromonas gingivalis and Tannerella forsythia are grouped into the red complex that is highly correlated with periodontal disease. Socransky's work closely associates red with orange complex species such as Fusobacterium nucleatum and Pre...

Posttranscriptional regulation of lung elastin production.

Elastin is a resilient connective-tissue protein present in the extracellular matrix of most vertebrate tissues, but because of its unique elastomeric properties, this connectivetissue component is especially abundant in the interstitium of tissues that undergo repetitive physical deformations, such as the walls of alveoli and blood vessels (1). Elastic fibers are assembled extracellularly and ...

Regulation of Vascular Function on Posttranscriptional Level

Posttranscriptional control of gene expression is crucial for regulating plurality of proteins and functional plasticity of the proteome under (patho)physiologic conditions. Alternative splicing as well as micro (mi)RNA-mediated mechanisms play an important role for the regulation of protein expression on posttranscriptional level. Both alternative splicing and miRNAs were shown to influence ca...

Posttranscriptional regulation of mammalian circadian clock output.

Circadian clocks are present in many different cell types/tissues and control many aspects of physiology. This broad control is exerted, at least in part, by the circadian regulation of many genes, resulting in rhythmic expression patterns of 5-10% of the mRNAs in a given tissue. Although transcriptional regulation is certainly involved in this process, it is becoming clear that posttranscripti...